Hedione HC
Fresh, Clean, Sweet, Floral, Jasmine. Diffusive & Fixative
About this material
Hedione HC Firmenich aka Hedione High Cis is a widely used fragrance ingredient in the perfume industry. It’s popularity stems from its ability to provide a fresh and airy scent.
Hedione® HC, a more potent, higher impact variant of Hedione, is particularly beneficial in masculine fragrances while still being versatile in its application, providing a fresh and petal-like impression.It’s versatility allows it to blend well with various other ingredients, making it a staple in many perfume formulations.
Hedione High Cis, like Hedione is often used in perfumes to enhance the longevity and diffusion of the fragrance.
It’s preference in the realm of fine fragrances is notable, although its efficacy in functional products is reduced due to its inclination to revert back to regular Hedione in acidic or alkaline environments.
According to Firmenich, Hedione High Cis embodies a unique and robust floral note reminiscent of magnolia blossoms, offering exceptional enhancement properties.
Its strength surpasses that of classical Hedione® due to its high cis concentration. Notably, this Firmenich version contains approximately 75% of the desired cis isomer, surpassing many competing products.
With its pleasant scent and performance benefits, Hedione High Cis continues to be a sought-after choice for perfumers worldwide.
The high cis predecessor; Hedione along with ISO E Super have to be two of the most widely used aroma chemicals in all of modern day perfumery.
Hedione is also known to subtly stimulate the human pheromone receptors, which may contribute to its appeal in perfumery.
The assumption that hedione is attractive was all but confirmed by a 2015 paper published in the journal NeuroImage by cell physiologists from Bochum and Dresden in Germany.
Chemists found that it activates the putative pheromone receptor VN1R1, located in the olfactory epithelium and one of five still left in humans out of hundreds that occur in other mammals.
It’s the first time that a scent has been known to activate the pheromone receptor in humans.
The scientists then analysed brain activity to find out if the scent could have an impact on the brain, comparing the results with the control scent phenylethyl alcohol, a traditional floral fragrance; it activated brain areas in the limbic system, a part of the brain associated with emotions, memory and motivation, more strongly than the control.
But even more significantly, hedione activated a specific area of the hypothalamus in women, which in turn ignites the endocrine system, promoting a response to sexual cues.
Master perfumer Arcadi Boix Camps wrote of hedione ‘the compound that without a doubt has most influenced modern perfumery and has allowed the great artists to develop their ideas with inspiration… it has become famous because it gives to compositions a delicate, fresh, smooth, radiant, warm, elegant character that blends well with all kinds of perfumes from floral-citrics to woody, chypre and oriental.’ Today, it’s fame is cemented in science as well as art, a true icon of both worlds.
For those not familiar with Hedione, the raw material would appear to have a fairly quiet odour by itself. It is a middle note molecule, almost undetectable from the bottle and best appreciated after appropriate dilution or when incorporated into a blend.
For the untrained nose, Hedione HC may be difficult to detect in isolation.
Scent character
Highlights from the material’s listed odour profile.
Note position
Top note · Heart note
Material character
A closer lookOdour strength
(recommend smelling in a 10% solution or less)
Listed qualitative strength
Tenacity / substantivity
72 hour(s)
at 100%
Listed reference conditions
Fragrance development
Top note · Heart note
Illustrative note development · no measured evaporation data
Molecular identity

C13H22O3
CAS-linked compound reference — Hedione
This compound record is linked to the explicitly recorded CAS number. It is not supplier confirmation of the supplied grade, purity, stereochemistry, isomer proportions or complete composition.
- Reference molecular weight
- 226.31 g/mol
- Reference IUPAC name
- methyl 2-(3-oxo-2-pentylcyclopentyl)acetate
More compound properties
Computed and structural reference properties for the named compound. These are not measured supplier specifications or properties of a complete dilution, mixture or batch.
- XLogP (computed)
- 2.7
- Exact mass (Da)
- 226.15689456
- Monoisotopic mass (Da)
- 226.15689456
- Topological polar surface area (Ų)
- 43.4
- Complexity
- 248
- Formal charge
- 0
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 3
- Rotatable bonds
- 7
- Heavy atoms
- 16
- Isotope atoms
- 0
- Atom stereocentres
- 2
- Bond stereocentres
- 0
- Covalent units
- 1
- SMILES
- CCCCCC1C(CCC1=O)CC(=O)OC
- InChI
- InChI=1S/C13H22O3/c1-3-4-5-6-11-10(7-8-12(11)14)9-13(15)16-2/h10-11H,3-9H2,1-2H3
- InChIKey
- KVWWIYGFBYDJQC-UHFFFAOYSA-N
Reference data checked 2026-10-27.
CAS 24851-98-7 · reference checked 2026-10-27.
Fragrance allergen reference
Generic regulatory reference only. This is not a supplier allergen declaration, measured composition, allergen-free claim or finished-product labelling assessment.
Raw-material reference based on recorded CAS numbers. A CAS match identifies a reference entry; it does not verify the supplied grade, composition, purity or finished-product compliance. Naturals, bases and mixtures require composition review.
European Union / Northern Ireland
No direct listed-entry CAS match in this jurisdiction’s held reference set. This does not mean the material is allergen-free. Constituents, grouped entries and natural-material composition may require further review.
Finished-cosmetic declaration thresholds: greater than 0.001% leave-on; greater than 0.01% rinse-off. Apply the current target-market rules to the actual complete formulation; no concentration is inferred here.
Commission Regulation (EU) 2023/1545 · Regulation (EU) 2023/1545 with 11 November 2025 corrigendum; checked 2026-10-26.
Held EU transition dates: placing noncompliant products on the market until 2026-07-31; making them available until 2028-07-31. Check applicability and current law for the intended market. 2025 corrigendum.
Great Britain
No direct listed-entry CAS match in this jurisdiction’s held reference set. This does not mean the material is allergen-free. Constituents, grouped entries and natural-material composition may require further review.
Finished-cosmetic declaration thresholds: greater than 0.001% leave-on; greater than 0.01% rinse-off. Apply the current target-market rules to the actual complete formulation; no concentration is inferred here.
Regulation (EC) No 1223/2009, Annex III (Great Britain) · legislation.gov.uk current text checked 2026-10-26.
Current supplier composition or allergen declarations are required to assess naturals, bases, mixtures and actual concentrations. Reference data checked 2026-10-26; bundle 2026-10-27. Supplementary private documents remain separate.
Product specification
| CAS number | 24851-98-7 |
|---|---|
| Odour description (decreasing) | Fresh, Clean, Sweet, Floral, Jasmine. Diffusive & Fixative |
| Odour strength | Medium (recommend smelling in a 10% solution or less) |
| Perfumery use | Up to 30% in the fragrance concentrateListed perfumery guidance; this is not an IFRA limit. |
| Substantivity | 72 hour(s) at 100% |
| Solvent | None |
| Physical state | Liquid |
| Synonyms | Methyl Dihydrojasmonate HC, Methyl Dihydrojasmonate High Cis |
Safety & handling
Not Hazardous According To EC 1272/2008
Datasheets & customer documents
Available documents are attached to eligible completed orders in your account.
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Supplementary documents are supplied only where explicitly listed and available. Check documentation information
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Documentation Supply PolicyIFRA formulation guide
Generic reference only — not an IFRA certificate, compliance decision or use recommendation. The Responsible Person and qualified safety assessor must assess the actual finished formula using current applicable IFRA Standards, supplementary documentation where available and the CPSR.
Raw-material reference based on recorded CAS numbers. A CAS match identifies a reference entry; it does not verify the supplied grade, composition, purity or finished-product compliance. Naturals, bases and mixtures require composition review.
Source: 51st Amendment overview, held source checked 2026-10-21. Bundle 2026-10-27. Individual Standards prevail over the overview.
No direct IFRA overview entry matched the recorded CAS in this held dataset. This does not mean unrestricted use, absence of relevant Standards or compliance. Constituent restrictions may still apply.
IFRA source overview · Individual IFRA Standards and supplementary documentation
Supplier certificates and private documents are separate evidence. Their availability does not determine whether this generic guide is shown. This is a dated local reference, not a live regulatory feed.
Creative ideas to explore
Creative directions, not tested formulas.Petals and peel
With bergamot and a light citrus ideaExplore a brighter version of the floral character using a simple citrus counterpoint. Compare it with the unchanged flower accord and note whether the citrus frames the bloom or becomes the main subject of the sketch.
Stem and blossom
With geranium and leafy notesSketch the flower with a greener setting, keeping leaf and blossom as distinct ideas. Compare a clean floral reference with the greener version to decide how much of the imagined stem and garden belongs in the composition.
Petals over wood
With a transparent wood directionPlace the floral material against a spare wood backdrop and follow the balance through the evaluation. Try a softer wood variation separately, then choose whether your flower needs an open, airy setting or a smoother, more enveloping frame.






Anonymous (verified owner) –
Excellent product as usual
Bradley (verified owner) –
Amazing product, as always!
Franca Tulino (verified owner) –
Yasser Ahmed (verified owner) –
suson.teodor (verified owner) –
Fresh, floral, and jasmine-like — adds brightness, diffusion, and natural elegance. A must-have for modern floral and musky compositions.