Odour strength
Not listed
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ISO E Super
Price range: £5.09 through £254.99
Odour description (decreasing): Velvety, Silky, Woody, Dry, Ambergris, Lemon, Floral. Diffusive & Fixative
- Description
- Additional information
- Reviews (4)
- Safety Information
- Datasheets
- Supplementary Documentation
- Disclaimer
About this material
ISO E Super is a highly sought-after fragrance ingredient known for its captivating aroma and versatility.
With its complex blend of woody, musky, and amber notes, ISO E Super adds depth and character to perfumes, colognes, and scented products.
Its unique molecular structure allows it to subtly enhance the scent, creating a long-lasting and memorable olfactory experience.
Whether used as a standalone note or as part of a fragrance composition, this beautiful hypnotic material brings a touch of sophistication and allure.
Discover the allure of this mesmerising fragrance compund and elevate your fragrance collection to new heights of elegance and refinement.
Iso E Super is a synthetic ketone fragrance aroma molecule, that is widely used in modern day perfumery and is responsible for showing up in modern day classic perfumes such as Christian Dior’s Sauvage and revolutionised when Escentric Molecules used this unique aroma molecule in their Molecule 01 perfume. We have created our own take on the well known Molecule 01 perfume using ISO E Super and you can find that here
It has a fairly quiet odour by itself. It is a long life heavy base note molecule with a large molecular structure, undetectable when smelt directly from the bottle or when applied to a test strip, so best appreciated after appropriate dilution or when incorporated into a blend.
Use to enhance the odour quality of most blends. Widespread belief is that it works like a pheromone, though not supported by research evidence, whereas Hedione for example is backed up by qualified research.
Higher impact forms of this material include Timbersilk and Sylvamber
You can read more about Iso E Super from IFF here: https://www.iff.com/en/scent/fragrance-ingredients/online-compendium#iso-e-super
For the untrained nose, ISO E Super may be difficult to detect in isolation.
Scent character
Highlights from the material’s listed odour profile.
VelvetySoft, tactile impression
SilkySmooth, flowing character
WoodyWood-toned character
Note position
Top note · Heart note · Base note
TopOpening impression
HeartMain fragrance character
BaseLasting foundation
Material character
A closer look
FixativeRecorded in this material profile
DiffusiveRecorded diffusion characteristic
Tenacity / substantivity
Not listed
Fragrance development
TopHeartBase
Top note · Heart note · Base note
Illustrative note development · no measured evaporation data
Generic material data
CAS-linked compound referenceMolecular identity
C16H26O
CAS-linked compound reference — 1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8-tetramethyl-2-naphthalenyl)ethanone
This compound record is linked to the explicitly recorded CAS number. It is not supplier confirmation of the supplied grade, purity, stereochemistry, isomer proportions or complete composition.
- Reference molecular weight
- 234.38 g/mol
- Reference IUPAC name
- 1-(2,3,8,8-tetramethyl-1,3,4,5,6,7-hexahydronaphthalen-2-yl)ethanone
More compound properties
Computed and structural reference properties for the named compound. These are not measured supplier specifications or properties of a complete dilution, mixture or batch.
- XLogP (computed)
- 3.6
- Exact mass (Da)
- 234.198365449
- Monoisotopic mass (Da)
- 234.198365449
- Topological polar surface area (Ų)
- 17.1
- Complexity
- 375
- Formal charge
- 0
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 1
- Heavy atoms
- 17
- Isotope atoms
- 0
- Atom stereocentres
- 2
- Bond stereocentres
- 0
- Covalent units
- 1
- SMILES
- CC1CC2=C(CC1(C)C(=O)C)C(CCC2)(C)C
- InChI
- InChI=1S/C16H26O/c1-11-9-13-7-6-8-15(3,4)14(13)10-16(11,5)12(2)17/h11H,6-10H2,1-5H3
- InChIKey
- FVUGZKDGWGKCFE-UHFFFAOYSA-N
Reference data checked 2026-10-27.
CAS 54464-57-2 · reference checked 2026-10-27.
Fragrance allergen reference
Generic regulatory reference only. This is not a supplier allergen declaration, measured composition, allergen-free claim or finished-product labelling assessment.
Raw-material reference based on recorded CAS numbers. A CAS match identifies a reference entry; it does not verify the supplied grade, composition, purity or finished-product compliance. Naturals, bases and mixtures require composition review.
European Union / Northern Ireland
- Tetramethyl Acetyloctahydronaphthalenes — Annex III entry 344; substance-group reference. Recorded CAS match only; composition and scope require assessment.
Finished-cosmetic declaration thresholds: greater than 0.001% leave-on; greater than 0.01% rinse-off. Apply the current target-market rules to the actual complete formulation; no concentration is inferred here.
Commission Regulation (EU) 2023/1545 · Regulation (EU) 2023/1545 with 11 November 2025 corrigendum; checked 2026-10-26.
Held EU transition dates: placing noncompliant products on the market until 2026-07-31; making them available until 2028-07-31. Check applicability and current law for the intended market. 2025 corrigendum.
Great Britain
No direct listed-entry CAS match in this jurisdiction’s held reference set. This does not mean the material is allergen-free. Constituents, grouped entries and natural-material composition may require further review.
Finished-cosmetic declaration thresholds: greater than 0.001% leave-on; greater than 0.01% rinse-off. Apply the current target-market rules to the actual complete formulation; no concentration is inferred here.
Regulation (EC) No 1223/2009, Annex III (Great Britain) · legislation.gov.uk current text checked 2026-10-26.
Current supplier composition or allergen declarations are required to assess naturals, bases, mixtures and actual concentrations. Reference data checked 2026-10-26; bundle 2026-10-27. Supplementary private documents remain separate.
Product specification
Physical stateLiquidReviewed product form
| CAS number | 54464-57-2 |
|---|---|
| Odour description (decreasing) | Velvety, Silky, Woody, Dry, Ambergris, Lemon, Floral. Diffusive & Fixative |
| Perfumery use | Up to 20%Listed perfumery guidance; this is not an IFRA limit. |
| Solvent | None |
| Physical state | Liquid |
| Synonyms | OTNE, Octahydrotetramethyl Acetophenone, Patchouli Ethanone, Tetramethyl Acetyloctahydronaphthalenes, Iso Gamma Super, Anthamber, Amber Fleur, Boisvelone, Iso Ambois, Amberlan, Iso Velvetone, Orbitone, Amberonne. |
Safety & handling
Listed handling information3 hazard statements9 precautions
Signal word: Warning
Hazard statements:
- H315 Causes skin irritation.
- H317 May cause an allergic skin reaction.
- H410 Very toxic to aquatic life with long lasting effects.
Precautionary statements:
- P264 Wash thoroughly after handling.
- P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
- P272 Contaminated work clothing should not be allowed out of the workplace.
- P273 Avoid release to the environment.
- P302+P352 IF ON SKIN: Wash with soap and water.
- P362 Take off contaminated clothing and wash before reuse.
- P333+P313 If skin irritation or a rash occurs: Get medical advice/attention.
- P501 Dispose of contents/ container in accordance with national regulations.
Professional/Industrial use only.
Datasheets & customer documents
Available documents are attached to eligible completed orders in your account.
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Supplementary documents are supplied only where explicitly listed and available. Check documentation information
Purchased as a guest? Follow the SDS request guidance in our Documentation Supply Policy and provide proof of purchase.
Documentation Supply PolicyIFRA formulation guide
Generic reference only — not an IFRA certificate, compliance decision or use recommendation. The Responsible Person and qualified safety assessor must assess the actual finished formula using current applicable IFRA Standards, supplementary documentation where available and the CPSR.
Raw-material reference based on recorded CAS numbers. A CAS match identifies a reference entry; it does not verify the supplied grade, composition, purity or finished-product compliance. Naturals, bases and mixtures require composition review.
Source: 51st Amendment overview, held source checked 2026-10-21. Bundle 2026-10-27. Individual Standards prevail over the overview.
1-(1,2,3,4,5,6,7,8 Octahydro-2,3,8,8-tetramethyl-2-naphthalenyl) ethanone (OTNE)
RESTRICTION · CAS 54464-57-2, 54464-59-4, 68155-66-8, 68155-67-9
Category 4 — fine fragrance: 20% in the finished consumer product
All applicable specification, purity and other Standard conditions must also be met.
All IFRA categories and Standard conditions
| Category 1 | 0.41% in the finished consumer product |
|---|---|
| Category 2 | 1.1% in the finished consumer product |
| Category 3 | 0.41% in the finished consumer product |
| Category 4 | 20% in the finished consumer product |
| Category 5A | 5.1% in the finished consumer product |
| Category 5B | 0.56% in the finished consumer product |
| Category 5C | 0.76% in the finished consumer product |
| Category 5D | 0.19% in the finished consumer product |
| Category 6 | 0.0093% in the finished consumer product |
| Category 7A | 0.67% in the finished consumer product |
| Category 7B | 0.67% in the finished consumer product |
| Category 8 | 0.19% in the finished consumer product |
| Category 9 | 2.4% in the finished consumer product |
| Category 10A | 2.4% in the finished consumer product |
| Category 10B | 6.6% in the finished consumer product |
| Category 11A | 0.19% in the finished consumer product |
| Category 11B | 0.19% in the finished consumer product |
| Category 12 | No numeric restriction in this overview cell; review the full Standard and other applicable requirements. |
CAS numbers (comment): The scope of this Standard includes, but is not limited to the CAS number(s) indicated above; any other CAS number(s) used to identify this fragrance ingredient should be considered in scope as well.
Contributions from other sources: None to consider
Flavor use consideration: Due to the possible ingestion of small amounts of fragrance ingredients from their use in products in Categories 1 and 6, materials must not only comply with IFRA Standards but must also be recognized as safe as a flavoring ingredient as defined by the IOFI Code of Practice (www.iofi.org). For more details see chapter 1 of the Guidance for the use of IFRA Standards.
IFRA Standard type: RESTRICTION
Intrinsic property driving the risk management measure: DERMAL SENSITIZATION AND SYSTEMIC TOXICITY
Amendment revised: 49
Existing creations deadline: February 10, 2022
New creations deadline: February 10, 2021
IFRA source overview · Individual IFRA Standards and supplementary documentation
Supplier certificates and private documents are separate evidence. Their availability does not determine whether this generic guide is shown. This is a dated local reference, not a live regulatory feed.
Creative ideas to explore
Creative directions, not tested formulas.
Woods in daylight
With bergamot and a crisp citrus openingExplore a spare wood structure with citrus providing the opening contrast. Compare a brighter version with the wood reference and follow how the outline changes, keeping the later impression as important as the first moment.
A softer grain
With sandalwood and a musk directionSet the woody material beside a softer wood reference, then compare a restrained musk variation. Decide whether your concept needs creamy texture, dry definition or more space between its parts before expanding the accord.
Petals on timber
With rose and a clear floral accordTry a flower-and-wood study in which both subjects remain recognisable. Compare the floral reference with the woody variation through the evaluation, noting whether the wood forms a useful backdrop or becomes the centre of the idea.
| Volume | 10ml, 30ml, 100ml, 250g, 500g, 1kg, 5kg |
|---|
Dilution Information
MaterialFragrance ingredient
Carrier / solventAs specified for the product
Supplied dilutionCheck the ratio and carrier
Concept illustration only; no dilution ratio or carrier is implied for this material. Refer to the product specification and label.
The suffix D forms part of the product name and indicates that the material is supplied as a dilution rather than at full strength.
POD = Precious Oil Dilution, typically intended for aromatherapy applications.
AOD = Absolute Oil Dilution, indicating that the product is supplied as a diluted absolute.
The dilution ratio and carrier/solvent are stated within the product specification and will also be shown on the product label.
IMPORTANT: Customers should always rely on the product specification when confirming the concentration and carrier/solvent supplied.
While we endeavour to ensure that product names and suffixes accurately reflect the material supplied, the product specification (including the stated dilution ratio and carrier/solvent) shall take precedence in the event of any omission, abbreviation, naming variation, or delayed update to a product title.
Please ensure you have selected the correct material, concentration, dilution ratio and carrier/solvent before completing your purchase.
4 reviews for ISO E Super
Handling precautions
For professional perfumery use only. Not for direct application to skin or ingestion. Keep out of reach of children.
Handle using the precautions specified for the material. Wear suitable protective gloves and eye protection where required.
Keep away from sources of ignition where applicable and avoid release to the environment.
Keep containers securely closed and store under the conditions specified on the product label and SDS. Keep liquid containers upright.
If swallowed or otherwise exposed, follow the SDS first-aid instructions and seek medical advice as appropriate. Do not induce vomiting unless directed by a medical professional.
Product-specific warnings, handling precautions and storage requirements take precedence over this general information.
Read the applicable SDS
A Safety Data Sheet (SDS) is available to logged in users who have purchased this item, where applicable.
Documents are not supplied before purchase.
Read the applicable SDS before handling or using the material. Follow its instructions for hazards, protective equipment, first aid, handling, storage and disposal.
An SDS provides information about the material supplied; it does not replace an assessment of the safety or compliance of a finished formulation.
Please note that supplementary documentation—including, but not limited to, IFRA Certificates, Certificates of Analysis (CoA), Allergen Declarations, and other regulatory or compositional data—may not be available for all products. Refer to the "Supplementary Documentation" tab to check current availability. If the tab is not present, no supplementary documents are available for the material.
Customers intending to use materials in cosmetic applications, including for the preparation of a Cosmetic Product Safety Report (CPSR) under UK and EU Cosmetics Regulations, must contact us prior to purchase to confirm the availability and suitability of any required documentation where it is not explicitly stated. Orders must not be placed in reliance on the assumption that such documentation will be provided where it is not explicitly stated on the relevant product page at the time of purchase.
By proceeding with a purchase without prior written confirmation, you acknowledge and accept that documentation beyond the legally required SDS may not be supplied, and you agree that Perfume Extract shall not be held liable for the absence of such documentation or for any inability to complete regulatory requirements, including CPSR or product compliance obligations.
Products are supplied in accordance with our Documentation Supply Policy
The following additional documentation is available as a download to logged in users who have purchased this item:
- IFRA
- ALLERGEN
Document scope and limitations
The supplementary documents currently available for this material are identified in this tab. Availability varies between materials.
Batch-specific certificates, analytical results and additional technical data are not guaranteed. They are supplied only where their availability is expressly confirmed in this tab or separately confirmed by us in writing.
Where provided, supplier IFRA documentation does not replace a comprehensive safety assessment or constitute approval of a finished formulation. Customers must consider their complete formulation and intended application.
Any linked IFRA standard is provided for reference and is not a batch-specific specification or analytical certificate for the material supplied.
Do not assume that documentation confirms a particular batch, residual constituent level, manufacturing process or analytical result unless it expressly states this.
The same limitations apply to allergen declarations, Certificates of Analysis (CoAs), technical data sheets, specifications, and other regulatory, analytical or compositional documents. These documents provide information only within their stated scope; they do not replace a comprehensive safety assessment or constitute approval of a finished formulation, nor do they guarantee suitability for a particular application. Customers must assess their complete formulation and intended use.
Customer responsibility
These limitations apply to reliance on all documentation supplied, including IFRA information, allergen declarations, Certificates of Analysis (CoAs), technical data sheets, specifications and other supporting documents.
Perfume Extract is solely a reseller of this product and is not an agent, official distributor, or affiliated in any way with the manufacturer.
Customers are responsible for determining whether the material and available documentation meet their requirements before purchase, and for assessing the safety and compliance of their finished products.
We do not provide formulation instructions, formulation consultancy or confirmation of suitability at a particular concentration or for a particular application.
Producer identity, detailed sourcing and processing information are not disclosed beyond the information published in the product listing.
Please read our Documentation Supply Policy alongside the product specification and available documentation.
Synonyms, alternative names, CAS/EC references, botanical names, manufacturer references and external links may describe a substance or material family generally. They should not, on their own, be taken as confirmation of the supplied material’s producer, geographical origin, manufacturing process, grade, purity, constituent levels or batch characteristics.
In particular, a synonym or reference must not be used to infer that a material is free from a particular constituent, meets a numerical specification, or is suitable for a particular application or concentration.
IFRA information, allergen declarations, Certificates of Analysis (CoAs), technical data sheets and other supporting documents apply only within their expressly stated scope. A general specification or reference document is not a batch-specific analytical result unless it expressly identifies the relevant batch.
If information appears inconsistent, or a particular characteristic is essential to your purchase, contact us for written clarification before ordering. Do not resolve discrepancies by assuming that a synonym, external reference or document for another grade applies to the material supplied.
We do not confirm characteristics beyond those expressly supported by the applicable product specification or our written confirmation. Customers remain responsible for assessing their complete formulation and intended application.
Nothing in this information excludes or restricts liability or statutory rights that cannot lawfully be excluded or restricted.
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Franca Tulino (verified owner) –
Simon Ilinkin (verified owner) –
Paul Ensell –
Staple ingredient that aids and supports so many other ingredients
Abbie Graham (verified owner) –
What is there not to like? It’s ISO E Super!