About this material
Caryophyllene; otherwise referred to as Beta-Caryophyllene is common in many natural oils.
With a wide range of fragrance uses, it is most used in spice blends, but also citrus flavors and in chewing gum.
It is a liquid with a softly spicy, woody, and dry elegance that adds a sparkling touch to scents like clove, pepper, and various florals.
With hints of Cananga, Cinnamon, Calamus, and Copaiba; as it dries down, a pleasantly musty driftwood note emerges.
The true value of caryophyllene lies not just in its scent, but in how it enhances and enriches florals and woods that require more dimension and diffusion. Thus, it is an excellent choice for opening a fragrance.
Adds a great spicy note that isn’t IFRA restricted like Eugenol.
Scent character
Highlights from the material’s listed odour profile.
Note position
Top note
Material character
A closer lookOdour strength
(recommend smelling in a 10.00 % solution or less)
Listed qualitative strength
Tenacity / substantivity
28 hour(s)
at 100%
Listed reference conditions
Fragrance development
Top note
Illustrative note development · no measured evaporation data
Molecular identity
C15H24
CAS-linked compound reference — (-)-Caryophyllene
This compound record is linked to the explicitly recorded CAS number. It is not supplier confirmation of the supplied grade, purity, stereochemistry, isomer proportions or complete composition.
- Reference molecular weight
- 204.35 g/mol
- Reference IUPAC name
- (1R,4E,9S)-4,11,11-trimethyl-8-methylidenebicyclo[7.2.0]undec-4-ene
More compound properties
Computed and structural reference properties for the named compound. These are not measured supplier specifications or properties of a complete dilution, mixture or batch.
- XLogP (computed)
- 4.4
- Exact mass (Da)
- 204.187800766
- Monoisotopic mass (Da)
- 204.187800766
- Topological polar surface area (Ų)
- 0
- Complexity
- 293
- Formal charge
- 0
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 0
- Rotatable bonds
- 0
- Heavy atoms
- 15
- Isotope atoms
- 0
- Atom stereocentres
- 2
- Bond stereocentres
- 1
- Covalent units
- 1
- SMILES
- C/C/1=C\CCC(=C)[C@H]2CC([C@@H]2CC1)(C)C
- InChI
- InChI=1S/C15H24/c1-11-6-5-7-12(2)13-10-15(3,4)14(13)9-8-11/h6,13-14H,2,5,7-10H2,1,3-4H3/b11-6+/t13-,14-/m1/s1
- InChIKey
- NPNUFJAVOOONJE-GFUGXAQUSA-N
Reference data checked 2026-10-27.
CAS 87-44-5 · reference checked 2026-10-27.
Fragrance allergen reference
Generic regulatory reference only. This is not a supplier allergen declaration, measured composition, allergen-free claim or finished-product labelling assessment.
Raw-material reference based on recorded CAS numbers. A CAS match identifies a reference entry; it does not verify the supplied grade, composition, purity or finished-product compliance. Naturals, bases and mixtures require composition review.
European Union / Northern Ireland
- Beta-Caryophyllene — Annex III entry 332; single-substance reference. Recorded CAS match only; composition and scope require assessment.
Finished-cosmetic declaration thresholds: greater than 0.001% leave-on; greater than 0.01% rinse-off. Apply the current target-market rules to the actual complete formulation; no concentration is inferred here.
Commission Regulation (EU) 2023/1545 · Regulation (EU) 2023/1545 with 11 November 2025 corrigendum; checked 2026-10-26.
Held EU transition dates: placing noncompliant products on the market until 2026-07-31; making them available until 2028-07-31. Check applicability and current law for the intended market. 2025 corrigendum.
Great Britain
No direct listed-entry CAS match in this jurisdiction’s held reference set. This does not mean the material is allergen-free. Constituents, grouped entries and natural-material composition may require further review.
Finished-cosmetic declaration thresholds: greater than 0.001% leave-on; greater than 0.01% rinse-off. Apply the current target-market rules to the actual complete formulation; no concentration is inferred here.
Regulation (EC) No 1223/2009, Annex III (Great Britain) · legislation.gov.uk current text checked 2026-10-26.
Current supplier composition or allergen declarations are required to assess naturals, bases, mixtures and actual concentrations. Reference data checked 2026-10-26; bundle 2026-10-27. Supplementary private documents remain separate.
Product specification
| CAS number | 87-44-5 |
|---|---|
| Odour description (decreasing) | Sweet, Spicy, Clove, Dry, Dusty, Oily, Woody, Tenacious |
| Odour strength | Medium (recommend smelling in a 10.00 % solution or less) |
| Perfumery use | Effective from the smallest traces, through to 8%Listed perfumery guidance; this is not an IFRA limit. |
| Substantivity | 28 hour(s) at 100% |
| Solvent | None |
| Physical state | Liquid |
| Synonyms | (1R, 4E, 9S)-4, 11, 11-trimethyl-8-methylidenebicyclo[7.2.0]undec-4-ene, beta-Caryophyllene, Trans-Caryo-phyllene, Bicyclo[7.2.0]undec-4-ene, 4,11,11-trimethyl-8-methylene- Humulene, |
Safety & handling
Signal word: Danger
Hazard statements:
- H304 May be fatal if swallowed and enters airways.
Precautionary statements:
- P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
- P331 Do NOT induce vomiting.
- P405 Store locked up.
- P501 Dispose of contents/container in accordance with local regulations.
Professional/Industrial use only.
Datasheets & customer documents
Available documents are attached to eligible completed orders in your account.
Sign in to view your ordersMy account → Orders
Supplementary documents are supplied only where explicitly listed and available. Check documentation information
Purchased as a guest? Follow the SDS request guidance in our Documentation Supply Policy and provide proof of purchase.
Documentation Supply PolicyIFRA formulation guide
Generic reference only — not an IFRA certificate, compliance decision or use recommendation. The Responsible Person and qualified safety assessor must assess the actual finished formula using current applicable IFRA Standards, supplementary documentation where available and the CPSR.
Raw-material reference based on recorded CAS numbers. A CAS match identifies a reference entry; it does not verify the supplied grade, composition, purity or finished-product compliance. Naturals, bases and mixtures require composition review.
Source: 51st Amendment overview, held source checked 2026-10-21. Bundle 2026-10-27. Individual Standards prevail over the overview.
No direct IFRA overview entry matched the recorded CAS in this held dataset. This does not mean unrestricted use, absence of relevant Standards or compliance. Constituent restrictions may still apply.
IFRA source overview · Individual IFRA Standards and supplementary documentation
Supplier certificates and private documents are separate evidence. Their availability does not determine whether this generic guide is shown. This is a dated local reference, not a live regulatory feed.
Creative ideas to explore
Creative directions, not tested formulas.Spice among petals
With rose and a clear floral accordExplore a floral study with the spicy material as the changing accent. Compare it against the flower alone, deciding whether the contrast suggests warmth, brightness or a more pronounced spice character that deserves a different brief.
Peel and spice
With bergamot and an aromatic directionSketch a brighter spice idea around citrus peel, then compare an herbal variation separately. Evaluate which setting makes the material’s listed character easiest to recognise and whether the opening still matches the composition you want to build.
A textured wood
With sandalwood and an amber directionPlace the spice character against a simple wood backdrop and compare a warmer amber variation. Keep the wood-only reference close so you can judge the contribution of each change without mistaking a richer blend for a better one.







rjrmagic (verified owner) –
Caryophyllene is one of those materials that does a lot of heavy lifting without shouting about it.
It’s warm, spicy and a bit woody.