About this material
Ambrettolide
Ambrettolide is a macrocyclic musk with exceptional diffusion and a very fine character. It is a key ingredient in the fragrance industry.
It’s unique scent profile and long-lasting properties make it a popular choice among perfumers.
This material is derived from the seeds of the hibiscus plant and possesses a musky, slightly floral aroma.
Ambrettolide is widely used in various personal care products, including perfumes, lotions, and soaps, due to its ability to enhance and prolong the fragrance.
Additionally, it serves as a fixative, helping the scent to adhere to the skin for an extended period.
The influence of this beautiful material in a composition can be perceived at all evaporation levels.
It is highly substantive, exalting the top note of a fragrance in an exceptional manner.
Scent character
Highlights from the material’s listed odour profile.
Note position
Top note · Heart note · Base note
Material character
A closer lookOdour strength
Not listed
Tenacity / substantivity
248 hour(s)
at 100%
Listed reference conditions
Supplied strength is 10% in DPG.
Fragrance development
Top note · Heart note · Base note
Illustrative note development · no measured evaporation data
Compound reference
Raw-material reference
This is a published reference for the named raw material. It is not a measured specification, supplier certificate or complete composition of the supplied product or dilution.
- Reference molecular formula
- C16H28O2
- Reference molecular weight
- 252.4 g/mol
Several compound records match this CAS. The published material formula and molecular weight are shown without selecting an individual isomer to represent the supplied grade or dilution.
Perfume Extract material reference · checked 2026-10-27. Supplier identity is not disclosed.
Fragrance allergen reference
Generic regulatory reference only. This is not a supplier allergen declaration, measured composition, allergen-free claim or finished-product labelling assessment.
Raw undiluted material reference. These data refer to the named active material, not the complete supplied dilution. A raw-material IFRA ceiling is not a use level for this diluted product. The assessor must account for the actual concentration, carrier and all other formula contributions.
European Union / Northern Ireland
No direct listed-entry CAS match in this jurisdiction’s held reference set. This does not mean the material is allergen-free. Constituents, grouped entries and natural-material composition may require further review.
Finished-cosmetic declaration thresholds: greater than 0.001% leave-on; greater than 0.01% rinse-off. Apply the current target-market rules to the actual complete formulation; no concentration is inferred here.
Commission Regulation (EU) 2023/1545 · Regulation (EU) 2023/1545 with 11 November 2025 corrigendum; checked 2026-10-26.
Held EU transition dates: placing noncompliant products on the market until 2026-07-31; making them available until 2028-07-31. Check applicability and current law for the intended market. 2025 corrigendum.
Great Britain
No direct listed-entry CAS match in this jurisdiction’s held reference set. This does not mean the material is allergen-free. Constituents, grouped entries and natural-material composition may require further review.
Finished-cosmetic declaration thresholds: greater than 0.001% leave-on; greater than 0.01% rinse-off. Apply the current target-market rules to the actual complete formulation; no concentration is inferred here.
Regulation (EC) No 1223/2009, Annex III (Great Britain) · legislation.gov.uk current text checked 2026-10-26.
Current supplier composition or allergen declarations are required to assess naturals, bases, mixtures and actual concentrations. Reference data checked 2026-10-26; bundle 2026-10-27. Supplementary private documents remain separate.
Product specification
| CAS number | 28645-51-4 |
|---|---|
| Odour description (decreasing) | Musky, Powerful, Warm, Ambrette Seed, Fruity |
| Perfumery use | Effective from the smallest traces up to 2% of the fragrance concentrateListed perfumery guidance; this is not an IFRA limit. |
| Substantivity | 248 hour(s) at 100% |
| Solvent | DPG to give a 10% solution of Ambrettolide |
| Physical state | Liquid |
| Synonyms | Hexadecimal-9-en-1, 16 lactone, isoambrettolide, Scentolide |
| IFRA document scope | Where an IFRA document is shared with the raw material, it refers to the raw, undiluted material. It is supplied as a reference for this diluted product; its stated limits are not limits for the supplied dilution. Check the document scope and assess the intended finished formulation. This notice does not confirm that a document is available. |
Safety & handling
Not Hazardous According To EC 1272/2008
Datasheets & customer documents
Available documents are attached to eligible completed orders in your account.
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Supplementary documents are supplied only where explicitly listed and available. Check documentation information
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Documentation Supply PolicyIFRA formulation guide
Generic reference only — not an IFRA certificate, compliance decision or use recommendation. The Responsible Person and qualified safety assessor must assess the actual finished formula using current applicable IFRA Standards, supplementary documentation where available and the CPSR.
Raw undiluted material reference. These data refer to the named active material, not the complete supplied dilution. A raw-material IFRA ceiling is not a use level for this diluted product. The assessor must account for the actual concentration, carrier and all other formula contributions.
Source: 51st Amendment overview, held source checked 2026-10-21. Bundle 2026-10-27. Individual Standards prevail over the overview.
No direct IFRA overview entry matched the recorded CAS in this held dataset. This does not mean unrestricted use, absence of relevant Standards or compliance. Constituent restrictions may still apply.
IFRA source overview · Individual IFRA Standards and supplementary documentation
Supplier certificates and private documents are separate evidence. Their availability does not determine whether this generic guide is shown. This is a dated local reference, not a live regulatory feed.
Creative ideas to explore
Creative directions, not tested formulas.A petal backdrop
With rose and a simple floral accordExplore the musk material as a setting for a familiar flower. Compare the flower alone and the musk variation through the evaluation, focusing on the texture you perceive and whether the flower remains distinct against its new backdrop.
Quiet woods
With sandalwood and transparent woodsBuild a spare wood-and-musk study with only a few moving parts. Compare soft and dry wood directions separately, then choose the combination whose balance feels closest to your intended outline instead of adding every appealing note.
Clean brightness
With bergamot and an airy floral ideaTry a brighter musk direction with citrus as the opening contrast. Assess it beside a matching reference without the citrus, noting how the clean, floral or woody aspects you actually perceive develop over the evaluation.






RJR (verified owner) –
Top quality Ambrettolide perfectly dosed at 10%
Anonymous (verified owner) –
Top quality product as always!