About this material
Ambroxan
Ambroxan is a highly powerful, substantive and stable amber note.
It’s a synthetic fragrance molecule known for its warm, woody, musky, and slightly sweet scent.
It is widely used in perfumery as a modern replacement for natural ambergris, which was historically derived from sperm whales.
Key Facts About Ambroxan
- Scent Profile: Smooth, warm, slightly sweet, woody, musky, and ambery. It enhances longevity and depth in fragrances.
- Origin: Originally derived from sclareol, a compound found in clary sage, but now fully synthesized for ethical and sustainability reasons.
- Uses in Perfumery:
- As a base note in many modern perfumes.
- Adds warmth and sensuality to fragrances.
- Enhances projection and longevity of other ingredients.
- Popular Perfumes Featuring Ambroxan:
- Dior Sauvage
- Juliette Has a Gun Not a Perfume
- Molecule 02 by Escentric Molecules
Commonly used for re-creating authentic ambergris notes in modern day perfumery.
Ambroxan adds a unique ‘effect’ to any perfume. Clean, crisp with a powdery depth; reminiscent of clean laundry.
Ambroxan is a crystallised solid in its pure form and concentrations of 10% and over can re-crystallise at room temperature, making it difficult to work with so here we provide a pre-dissolved solution in DPG for your convenience. We have a 10% solution available here or the pure crystal form available here if you prefer to work with the solid form of this material.
For the untrained nose, Ambroxan may be difficult to detect in isolation.
Scent character
Highlights from the material’s listed odour profile.
Note position
Base note
Material character
A closer lookOdour strength
, recommend smelling in a 1% solution or less
Listed qualitative strength
Tenacity / substantivity
> 400 hour(s) at 10% in DPG
Listed reference conditions
Supplied strength is 5% in DPG.
Fragrance development
Base note
Illustrative note development · no measured evaporation data
Molecular identity

C16H28O
CAS-linked compound reference — (-)-Ambroxide
Historical CAS reference: The catalogue records CAS 254762-72-6. The compound reference marks it as deprecated and lists current CAS 6790-58-5 for this compound record. This is an explicit historical-identifier reference, not a change to the recorded product identity. Confirm current supplier identifiers before any stock identity change.
This compound record is linked to the explicitly recorded CAS number. It is not supplier confirmation of the supplied grade, purity, stereochemistry, isomer proportions or complete composition.
Named active material only. These properties do not describe the complete supplied dilution or carrier.
- Reference molecular weight
- 236.39 g/mol
- Reference IUPAC name
- (3aR,5aS,9aS,9bR)-3a,6,6,9a-tetramethyl-2,4,5,5a,7,8,9,9b-octahydro-1H-benzo[e][1]benzofuran
More compound properties
Computed and structural reference properties for the named compound. These are not measured supplier specifications or properties of a complete dilution, mixture or batch.
- XLogP (computed)
- 4.7
- Exact mass (Da)
- 236.214015512
- Monoisotopic mass (Da)
- 236.214015512
- Topological polar surface area (Ų)
- 9.2
- Complexity
- 321
- Formal charge
- 0
- Hydrogen bond donors
- 0
- Hydrogen bond acceptors
- 1
- Rotatable bonds
- 0
- Heavy atoms
- 17
- Isotope atoms
- 0
- Atom stereocentres
- 4
- Bond stereocentres
- 0
- Covalent units
- 1
- SMILES
- C[C@]12CCCC([C@@H]1CC[C@@]3([C@@H]2CCO3)C)(C)C
- InChI
- InChI=1S/C16H28O/c1-14(2)8-5-9-15(3)12(14)6-10-16(4)13(15)7-11-17-16/h12-13H,5-11H2,1-4H3/t12-,13+,15-,16+/m0/s1
- InChIKey
- YPZUZOLGGMJZJO-LQKXBSAESA-N
Reference data checked 2026-10-27.
CAS 254762-72-6 · reference checked 2026-10-27.
Fragrance allergen reference
Generic regulatory reference only. This is not a supplier allergen declaration, measured composition, allergen-free claim or finished-product labelling assessment.
Raw undiluted material reference. These data refer to the named active material, not the complete supplied dilution. A raw-material IFRA ceiling is not a use level for this diluted product. The assessor must account for the actual concentration, carrier and all other formula contributions.
European Union / Northern Ireland
No direct listed-entry CAS match in this jurisdiction’s held reference set. This does not mean the material is allergen-free. Constituents, grouped entries and natural-material composition may require further review.
Finished-cosmetic declaration thresholds: greater than 0.001% leave-on; greater than 0.01% rinse-off. Apply the current target-market rules to the actual complete formulation; no concentration is inferred here.
Commission Regulation (EU) 2023/1545 · Regulation (EU) 2023/1545 with 11 November 2025 corrigendum; checked 2026-10-26.
Held EU transition dates: placing noncompliant products on the market until 2026-07-31; making them available until 2028-07-31. Check applicability and current law for the intended market. 2025 corrigendum.
Great Britain
No direct listed-entry CAS match in this jurisdiction’s held reference set. This does not mean the material is allergen-free. Constituents, grouped entries and natural-material composition may require further review.
Finished-cosmetic declaration thresholds: greater than 0.001% leave-on; greater than 0.01% rinse-off. Apply the current target-market rules to the actual complete formulation; no concentration is inferred here.
Regulation (EC) No 1223/2009, Annex III (Great Britain) · legislation.gov.uk current text checked 2026-10-26.
Current supplier composition or allergen declarations are required to assess naturals, bases, mixtures and actual concentrations. Reference data checked 2026-10-26; bundle 2026-10-27. Supplementary private documents remain separate.
Product specification
| CAS number | 254762-72-6 |
|---|---|
| Odour description (decreasing) | Amber, Ambergris, Woody, Dry, Clean, Diffusive & Fixative |
| Odour strength | High, recommend smelling in a 1% solution or less |
| Perfumery use | Effective from the smallest traces, through to 1% and lasts for over a month on a smelling strip.Listed perfumery guidance; this is not an IFRA limit. |
| Substantivity | > 400 hour(s) at 10% in DPG |
| Solvent | DPG to give a 5% solution of Ambroxan |
| Physical state | Liquid |
| Synonyms | Ambrox, Ambroxide, Ambrofix, (3aR,5aS,9aS,9bR)-3a,6,6,9a-tetramethyl-2,4,5,5a,7,8,9,9b-octahydro-1H-benzo[e][1]benzofuran |
| IFRA document scope | Where an IFRA document is shared with the raw material, it refers to the raw, undiluted material. It is supplied as a reference for this diluted product; its stated limits are not limits for the supplied dilution. Check the document scope and assess the intended finished formulation. This notice does not confirm that a document is available. |
Safety & handling
Not Hazardous According To EC 1272/2008
Professional/Industrial use only.
Datasheets & customer documents
Available documents are attached to eligible completed orders in your account.
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Supplementary documents are supplied only where explicitly listed and available. Check documentation information
Purchased as a guest? Follow the SDS request guidance in our Documentation Supply Policy and provide proof of purchase.
Documentation Supply PolicyIFRA formulation guide
Generic reference only — not an IFRA certificate, compliance decision or use recommendation. The Responsible Person and qualified safety assessor must assess the actual finished formula using current applicable IFRA Standards, supplementary documentation where available and the CPSR.
Raw undiluted material reference. These data refer to the named active material, not the complete supplied dilution. A raw-material IFRA ceiling is not a use level for this diluted product. The assessor must account for the actual concentration, carrier and all other formula contributions.
Source: 51st Amendment overview, held source checked 2026-10-21. Bundle 2026-10-27. Individual Standards prevail over the overview.
No direct IFRA overview entry matched the recorded CAS in this held dataset. This does not mean unrestricted use, absence of relevant Standards or compliance. Constituent restrictions may still apply.
IFRA source overview · Individual IFRA Standards and supplementary documentation
Supplier certificates and private documents are separate evidence. Their availability does not determine whether this generic guide is shown. This is a dated local reference, not a live regulatory feed.
Creative ideas to explore
Creative directions, not tested formulas.Amber in daylight
With bergamot and dry woodsExplore a brighter amber sketch with a citrus opening and a dry wood outline. Compare a spare version with a richer one, checking whether the amber character remains legible once the opening has moved on.
Petals after dark
With rose and a restrained spice ideaPlace the amber direction around a familiar rose accord. Add the spice idea as a separate variation, then compare both against the flower alone to decide whether you prefer warmth, contrast or a clearer floral centre.
Soft resin study
With resinous and vanilla directionsSketch a rounded amber using resinous and vanilla references as separate creative options. Compare the sweetness and texture of each, then decide whether your imagined amber should suggest dry balsam, soft vanilla or a balance between them.






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Antonio Turiello – Sky Princess – Technical dept. Turiello (verified owner) –
Light and sweet ambergris fixative, very stunning stuff !!