ISO E Super TOCO IFF

ISO E Super TOCO by IFF is a modern masterpiece of fragrance chemistry; a luxurious, woody-amber molecule prized for its smooth, velvety, sophisticated scent and remarkable versatility.

This enhanced version of the iconic Iso E Super includes a touch of tocopherol as supplied by IFF, added to improve stability, prevent oxidation, and maintain purity over time.

The result is a beautifully consistent ingredient that performs impeccably across fine fragrances, colognes, and scented body products.

Its scent is velvety, musky, and amber-woody, with an almost magnetic softness that lingers on the skin.

While subtle on its own, ISO E Super TOCO reveals its full character in blends; adding depth, warmth, and diffusion to compositions and enhancing other notes without overpowering them.

A true cornerstone of modern perfumery, Iso E Super has been used in iconic creations such as Dior Sauvage and was revolutionized by Escentric Molecules’ Molecule 01.

For the untrained nose, ISO E Super TOCO may be barely perceptible; yet it leaves an unmistakable trail of sophistication that lingers long after the first impression.

While some believe ISO E Super has pheromonal qualities, this remains anecdotal; unlike Hedione, whose sensual effects are supported by research.

For perfumers seeking even greater impact, related materials include Timbersilk and Sylvamber, both offering intensified woody-amber characters that are based on the same DNA.

In summary, the inclusion of tocopherol helps maintain the integrity of the fragrance molecule during storage, processing, or in challenging formulation matrices (e.g. heat, light, air exposure).

Because the difference lies primarily in stability and longevity rather than a change in scent profile, perfumers using ISO E Super TOCO can expect the same olfactive beauty as the original — but with greater confidence in its resistance to oxidation, discoloration, and degradation over time. This enhanced reliability makes it a highly sought-after choice among perfumers dedicated to crafting exceptional, long-lasting creations of uncompromising quality.

Learn more about Iso E Super on the IFF website →

Product specification.

CAS No: 68155-66-8
Odour description (decreasing): Velvety, Silky, Woody, Dry, Amber, Musky, Smooth, Warm. Diffusive & Fixative
Odour strength: Medium – soft but diffusive; long-lasting base note
Usage: Effective from the smallest traces up to 21.4%
Threshold: Low odour threshold (detectable at trace levels in blends)
Substantivity: 48 hour(s) at 100%
Solvent: None
Synonyms: OTNE, Octahydrotetramethyl Acetophenone, Patchouli Ethanone, Tetramethyl Acetyloctahydronaphthalenes, Iso Gamma Super, Anthamber, Amber Fleur, Boisvelone, Iso Ambois, Amberlan, Iso Velvetone, Orbitone, Amberonne.
Name: 1-(1,2,3,4,5,6,7,8-Octahydro-2,3,8,8-tetramethyl-2-naphthyl)ethan-1-one
Molecular Formula: C₁₆H₂₆O
IFRA: 

Signal word: Warning

Contains: Tetramethyl Acetyloctahydronaphthalenes (68155-66-8, 54464-57-2, 68155-67-9, 54464-59-4), Tocopherol (10191-41-0)

Hazard statements:

• H315 Causes skin irritation.
• H317 May cause an allergic skin reaction.
• H410 Very toxic to aquatic life with long lasting effects.

Precautionary statements:

• P261 Avoid breathing mist or vapours.
• P264 Wash skin thoroughly after handling.
• P280 Wear protective gloves.
• P333+P313 If skin irritation or rash occurs: Get medical advice/ attention.
• P391 Collect spillage.
• P501 Dispose of contents/ container to an approved waste disposal plant.

Professional/Industrial use only.